Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 6/20 | 0.48 |
| ▸ | PPIB | P23284 | 3/20 | 0.47 |
| ▸ | PPIG | Q13427 | 2/20 | 0.47 |
| ▸ | PPIA | P62937 | 1/20 | 0.47 |
| ▸ | NPY1R | P25929 | 8/20 | 0.45 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CASR | P41180 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6895115 | 1.00 | PPID (0.48) | PPIDPPIBPPIGPPIANPY1R | |
| Trifluoroacetic Acid SCHEMBL4699162 | 0.96 | PPID (0.45) | PPIDPPIBPPIGPPIANPY1R | |
| SCHEMBL8612537 | 0.90 | NPY1R (0.42) | PPIDPPIBPPIGPPIANPY1R | |
| SCHEMBL6900118 | 0.89 | NPY1R (0.40) | NPY1RCASRMEN1KMT2A | |
| SCHEMBL8526447 | 0.89 | TPSAB1 (0.37) | PPIBNPY1RNPFFR1CASRMEN1 | |
| SCHEMBL6897697 | 0.87 | TPSAB1 (0.38) | NPY1RCYP2D6CASRMEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL7040972 | 0.87 | NPY1R (0.38) | NPY1RNPFFR1 | |
| Trifluoroacetic Acid SCHEMBL7038182 | 0.86 | NPY1R (0.43) | NPY1RNPFFR1 | |
| Trifluoroacetic Acid SCHEMBL8527977 | 0.86 | NPY1R (0.43) | NPY1R | |
| SCHEMBL8528714 | 0.85 | TPSAB1 (0.38) | NPY1RCASRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1337257-A4 | USE OF NEUROPEPTIDE-Y ANTAGONISTS IN TREATMENT OF ALCOHOLISM | UNIV CALIFORNIA (US) | 2004-04-07 | — | — | EP | disclosed |
| EP-1337257-A1 | USE OF NEUROPEPTIDE-Y ANTAGONISTS IN TREATMENT OF ALCOHOLISM | The Regents of the University of California (US) | 2003-08-27 | — | — | EP | disclosed |
| WO-2002028393-A1 | USE OF NEUROPEPTIDE-Y ANTAGONISTS IN TREATMENT OF ALCOHOLISM | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2002-04-11 | — | — | WO | disclosed |