Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 9/20 | 0.38 |
| ▸ | FAP | Q12884 | 4/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | ECE1 | P42892 | 1/20 | 0.36 |
| ▸ | ACKR3 | P25106 | 4/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4699255 | 1.00 | DPP4 (0.38) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL13316340 | 0.83 | APP (0.48) | ACKR3APPHTR1AADRA2ADRD2 | |
| SCHEMBL13349539 | 0.83 | APP (0.48) | ACKR3APPHTR1AADRA2ADRD2 | |
| SCHEMBL3539175 | 0.83 | APP (0.48) | ACKR3APPHTR1AADRA2ADRD2 | |
| SCHEMBL3539178 | 0.83 | APP (0.48) | ACKR3APPHTR1AADRA2ADRD2 | |
| SCHEMBL4752280 | 0.82 | ALDH1A1 (0.39) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL14601232 | 0.82 | ALDH1A1 (0.39) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL5576370 | 0.82 | ALDH1A1 (0.39) | DPP4FAPDPP8DPP9DPP7 | |
| Hydrochloric Acid SCHEMBL4752278 | 0.81 | ALDH1A1 (0.38) | DPP4GPR119 | |
| Hydrochloric Acid SCHEMBL4752275 | 0.81 | ALDH1A1 (0.38) | DPP4GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1909575-A2 | SUBSTITUTED N-CINNAMYL BENZAMIDES | ChemoCentryx Inc (US) | 2008-04-16 | — | — | EP | disclosed |
| US-20070021484-A1 | Substituted N-cinnamyl benzamides | CHEMOCENTRYX, INC. (US) | 2007-01-25 | — | — | US | disclosed |
| US-20070021484-A1 | Substituted N-cinnamyl benzamides | CHEMOCENTRYX, INC. (US) | 2007-01-25 | — | — | US | disclosed |
| WO-2007002842-A2 | SUBSTITUTED N-CINNAMYL BENZAMIDES | CHEMOCENTRYX, INC. (US) | 2007-01-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021484-A1 | Substituted N-cinnamyl benzamides | BRDT, BCCIP, NAT10 | DPP4 1165/4885FAP 791/4885DPP8 797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.