Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.68 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.67 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4699986 | 1.00 | DPP4 (0.68) | DPP4DPP7CYP3A4DPP9 | |
| SCHEMBL24244598 | 0.89 | DPP4 (0.79) | DPP4DPP7CYP3A4DPP9 | |
| SCHEMBL28434489 | 0.89 | DPP4 (0.79) | DPP4DPP7CYP3A4DPP9 | |
| SCHEMBL25840236 | 0.88 | DPP4 (0.77) | DPP4DPP7CYP3A4DPP9 | |
| SCHEMBL21985110 | 0.85 | DPP4 (0.88) | DPP4DPP7CYP3A4DPP9 | |
| SCHEMBL21985113 | 0.85 | DPP4 (0.84) | DPP4DPP7CYP3A4DPP9 | |
| SCHEMBL21985109 | 0.85 | DPP4 (0.88) | DPP4DPP7CYP3A4DPP9 | |
| SCHEMBL21985108 | 0.85 | DPP4 (0.68) | DPP4DPP7CYP3A4DPP9 | |
| SCHEMBL29142108 | 0.85 | DPP4 (0.68) | DPP4DPP7CYP3A4DPP9 | |
| SCHEMBL21985114 | 0.85 | DPP4 (0.84) | DPP4DPP7CYP3A4DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1973918-A2 | DERIVATIVES OF BETA-AMINO ACID AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS | RANBAXY LABORATORIES, LTD. (IN) | 2008-10-01 | — | — | EP | claimed |
| WO-2007077508-A2 | DERIVATIVES OF BETA-AMINO ACID AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2007-07-12 | — | — | WO | claimed |
| EP-1973918-A2 | DERIVATIVES OF BETA-AMINO ACID AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS | RANBAXY LABORATORIES, LTD. (IN) | 2008-10-01 | — | — | EP | disclosed |
| WO-2007077508-A2 | DERIVATIVES OF BETA-AMINO ACID AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2007-07-12 | — | — | WO | disclosed |