Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.77 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.69 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.68 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24244598 | 0.99 | DPP4 (0.79) | DPP4DPP7DPP8CYP3A4DPP9 | |
| SCHEMBL28434489 | 0.99 | DPP4 (0.79) | DPP4DPP7DPP8CYP3A4DPP9 | |
| SCHEMBL4699518 | 0.88 | DPP4 (0.68) | DPP4DPP7CYP3A4DPP9 | |
| SCHEMBL4699986 | 0.88 | DPP4 (0.68) | DPP4DPP7CYP3A4DPP9 | |
| SCHEMBL21985104 | 0.86 | DPP4 (0.68) | DPP4DPP7CYP3A4DPP9 | |
| SCHEMBL21985109 | 0.86 | DPP4 (0.88) | DPP4DPP7DPP8CYP3A4DPP9 | |
| SCHEMBL21985113 | 0.86 | DPP4 (0.84) | DPP4DPP7CYP3A4DPP9 | |
| SCHEMBL21985108 | 0.86 | DPP4 (0.68) | DPP4DPP7CYP3A4DPP9 | |
| SCHEMBL21985114 | 0.86 | DPP4 (0.84) | DPP4DPP7CYP3A4DPP9 | |
| SCHEMBL21985110 | 0.86 | DPP4 (0.88) | DPP4DPP7DPP8CYP3A4DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4050102-B1 | TRANSAMINASE MUTANT AND USE THEREOF IN PREPARATION OF SITAGLIPTIN INTERMEDIATE | ZHEJIANG YONGTAI TECHNOLOGY CO LTD (CN) | 2026-03-11 | — | — | EP | claimed |
| EP-4050102-B1 | TRANSAMINASE MUTANT AND USE THEREOF IN PREPARATION OF SITAGLIPTIN INTERMEDIATE | ZHEJIANG YONGTAI TECHNOLOGY CO LTD (CN) | 2026-03-11 | — | — | EP | disclosed |
| US-20230203550-A1 | USE OF STEREOSELECTIVE TRANSAMINASE IN ASYMMETRIC SYNTHESIS OF CHIRAL AMINE | ABIOCHEM BIOTECHNOLOGY CO., LTD (CN) | 2023-06-29 | — | — | US | disclosed |
| EP-4050102-A1 | TRANSAMINASE MUTANT AND USE THEREOF IN PREPARATION OF SITAGLIPTIN INTERMEDIATE | Zhejiang Yongtai Technology Co., Ltd. (CN) | 2022-08-31 | — | — | EP | disclosed |
| CN-108866021-A | A kind of transaminase mutant and preparing the application in sitagliptin intermediate | 浙江工业大学 | 2018-11-23 | — | — | CN | disclosed |