Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10110940 | 0.98 | TAAR1 (0.49) | TAAR1NR3C1NR3C2NPC1RAB9A | |
| SCHEMBL14286922 | 0.97 | TAAR1 (0.50) | TAAR1NR3C1NR3C2NPC1RAB9A | |
| SCHEMBL12601888 | 0.89 | TAAR1 (0.53) | TAAR1NR3C1NR3C2NPC1RAB9A | |
| SCHEMBL12601886 | 0.78 | TAAR1 (0.47) | TAAR1NR3C1NR3C2NPC1RAB9A | |
| SCHEMBL38652213 | 0.78 | TAAR1 (0.57) | TAAR1NPC1RAB9AALDH1A1TSHR | |
| SCHEMBL12952724 | 0.78 | TAAR1 (0.57) | TAAR1NPC1RAB9AALDH1A1TSHR | |
| SCHEMBL9051355 | 0.77 | IGF1R (0.50) | TAAR1NPC1ALDH1A1POLBCYP3A4 | |
| SCHEMBL11237534 | 0.77 | TAAR1 (0.55) | TAAR1NPC1RAB9AALDH1A1TSHR | |
| SCHEMBL11497278 | 0.76 | MGLL (0.49) | TAAR1ALDH1A1MGLLHPGD | |
| SCHEMBL6207760 | 0.76 | TSHR (0.57) | TAAR1NPC1RAB9ATSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981846-A2 | MARKERS, METHOD FOR MANUFACTURING THEM AND THEIR APPLICATIONS | Laboratoires Synth-Innove (FR) | 2008-10-22 | — | — | EP | disclosed |
| US-20080004360-A1 | Polyarylene Polymer And Use Thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-01-03 | — | — | US | disclosed |
| WO-2007017602-A2 | MARQUEURS, LEUR PROCEDE DE FABRICATION ET LEURS APPLICATIONS | LABORATOIRES SYNTH-INNOVE (FR) | 2007-02-15 | — | — | WO | disclosed |