Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 17/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3362854 | 0.84 | CRHR1 (0.44) | CRHR1 | |
| SCHEMBL4702339 | 0.80 | CRHR1 (0.44) | CRHR1 | |
| SCHEMBL4700568 | 0.77 | CRHR1 (0.41) | CRHR1 | |
| SCHEMBL13538501 | 0.76 | CHRM1 (0.42) | CRHR1 | |
| SCHEMBL4700572 | 0.75 | CRHR1 (0.41) | CRHR1 | |
| SCHEMBL3365798 | 0.74 | CRHR1 (0.49) | CRHR1 | |
| SCHEMBL4700566 | 0.74 | CRHR1 (0.65) | CRHR1 | |
| Hydrochloric Acid SCHEMBL4702272 | 0.73 | CRHR1 (0.64) | CRHR1 | |
| Hydrochloric Acid SCHEMBL7062792 | 0.73 | CRHR1 (0.42) | CRHR1 | |
| SCHEMBL3362846 | 0.72 | CRHR1 (0.55) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569911-B1 | INDAZOLE DERIVATIVES AS CRF ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2008-07-02 | — | — | EP | claimed |