Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL915707 | 1.00 | LMNA (0.33) | LMNAANPEPENPEPALDH1A1PLG | |
| SCHEMBL915730 | 0.92 | LMNA (0.41) | LMNAANPEPENPEPALDH1A1 | |
| SCHEMBL4699739 | 0.92 | LMNA (0.41) | LMNAANPEPENPEPALDH1A1 | |
| SCHEMBL915947 | 0.90 | ANPEP (0.36) | LMNAANPEPENPEPPLGPLAT | |
| SCHEMBL917197 | 0.88 | LMNA (0.33) | LMNAALDH1A1 | |
| SCHEMBL914994 | 0.88 | ANPEP (0.33) | LMNAANPEPENPEPALDH1A1PLG | |
| SCHEMBL4699450 | 0.88 | ANPEP (0.33) | LMNAANPEPENPEPALDH1A1PLG | |
| SCHEMBL914979 | 0.87 | ANPEP (0.32) | LMNAANPEPENPEPALDH1A1PLG | |
| SCHEMBL4700077 | 0.87 | ANPEP (0.32) | LMNAANPEPENPEPALDH1A1PLG | |
| SCHEMBL2973374 | 0.86 | ANPEP (0.31) | LMNAANPEPENPEPALDH1A1PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011028234-A1 | USES OF ACYLOXYALKYL CARBAMATE PRODRUGS OF TRANEXAMIC ACID | XENOPORT, INC. (US) | 2011-03-10 | — | — | WO | disclosed |
| EP-1919859-A2 | ACYLOXYALKYL CARBAMATE PRODRUGS OF TRANEXAMIC ACID, METHODS OF SYNTHESIS AND USE | Xenoport, Inc. (US) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007002013-A2 | ACYLOXYALKYL CARBAMATE PRODRUGS OF TRANEXAMIC ACID, METHODS OF SYNTHESIS AND USE | XENOPORT, INC. (US) | 2007-01-04 | — | — | WO | disclosed |