Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 18/20 | 0.53 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15556841 | 0.92 | TTK (0.56) | TTK | |
| SCHEMBL17590107 | 0.88 | TTK (0.58) | TTKFYNMAPK8MAPK10 | |
| SCHEMBL10279537 | 0.88 | TTK (0.60) | TTK | |
| SCHEMBL470206 | 0.85 | TTK (0.65) | TTK | |
| SCHEMBL470067 | 0.84 | TTK (0.55) | TTKFYN | |
| SCHEMBL17590110 | 0.82 | TTK (0.67) | TTKFYNMAPK8MAPK10 | |
| SCHEMBL470336 | 0.82 | TTK (0.42) | TTKFYN | |
| SCHEMBL463499 | 0.81 | TTK (0.59) | TTK | |
| SCHEMBL470082 | 0.81 | TTK (0.67) | TTK | |
| SCHEMBL15556387 | 0.81 | TTK (0.60) | TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012032031-A1 | SUBSTITUTED IMIDAZOPYRIDAZINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-03-15 | — | — | WO | disclosed |