Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.36 |
| ▸ | EDNRA | P25101 | 3/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 2/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | EDNRB | P24530 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3577481 | 0.87 | EPHX2 (0.36) | EPHX2EDNRAHRH3KCNH2PARP10 | |
| SCHEMBL3567412 | 0.86 | MAPT (0.42) | MAOB | |
| SCHEMBL4912750 | 0.84 | EPHX2 (0.41) | EPHX2HRH3KCNH2PARP10PPARG | |
| SCHEMBL4914765 | 0.83 | ACACB (0.39) | EDNRAHRH3KCNH2ACACB | |
| SCHEMBL4922019 | 0.81 | EPHX2 (0.36) | EPHX2HRH3KCNH2PARP10MAPK8 | |
| SCHEMBL4922516 | 0.80 | EPHX2 (0.44) | EPHX2PPARG | |
| SCHEMBL3583067 | 0.80 | KMO (0.38) | EDNRAHRH3KCNH2PPARGAPP | |
| SCHEMBL3003353 | 0.80 | HRH3 (0.39) | HRH3KCNH2 | |
| SCHEMBL4922648 | 0.78 | MEN1 (0.37) | EPHX2EDNRAACACBPPARG | |
| SCHEMBL3571629 | 0.77 | EGLN1 (0.40) | KCNH2ACACBMAPK8APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778632-B1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2008-08-20 | — | — | EP | disclosed |