Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 5/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4697797 | 0.82 | GCK (0.41) | MAPTPOLBTP53 | |
| SCHEMBL3014804 | 0.71 | APP (0.34) | MAPTTP53MAOAMAOBHRH3 | |
| SCHEMBL4924442 | 0.71 | MAPT (0.52) | MAPTPOLBTP53PKMHSD17B10 | |
| SCHEMBL4700830 | 0.71 | MCHR1 (0.38) | TP53 | |
| SCHEMBL333883 | 0.69 | FAAH (0.38) | MAOAMAOB | |
| SCHEMBL334231 | 0.68 | PPARG (0.41) | MAPTTP53 | |
| SCHEMBL3573660 | 0.67 | FAAH (0.40) | MAPTMAOAMAOBHRH3 | |
| SCHEMBL3013914 | 0.67 | P2RY14 (0.37) | MAOAMAOB | |
| SCHEMBL3012527 | 0.67 | PPARA (0.38) | MAPT | |
| SCHEMBL4700751 | 0.67 | GCK (0.41) | MAPTMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778633-B1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2008-12-03 | — | — | EP | disclosed |