Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 15/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4702087 | 0.92 | FGFR1 (0.48) | KMT2AFGFR1NPC1MEN1HPGD | |
| SCHEMBL2653245 | 0.89 | KMT2A (0.51) | KMT2AFGFR1NPC1MEN1HPGD | |
| SCHEMBL2654163 | 0.88 | KMT2A (0.47) | KMT2AFGFR1NPC1MEN1HPGD | |
| SCHEMBL2653620 | 0.88 | KMT2A (0.49) | KMT2AFGFR1NPC1MEN1HPGD | |
| SCHEMBL2652333 | 0.87 | FGFR1 (0.54) | KMT2AFGFR1NPC1MEN1HPGD | |
| SCHEMBL2652876 | 0.87 | KMT2A (0.49) | KMT2AFGFR1NPC1MEN1HPGD | |
| SCHEMBL2653616 | 0.86 | KMT2A (0.50) | KMT2AFGFR1NPC1MEN1HPGD | |
| SCHEMBL2648585 | 0.84 | HPGD (0.49) | KMT2AFGFR1NPC1HPGDSMN1; SMN2 | |
| SCHEMBL4704314 | 0.83 | FGFR1 (0.51) | KMT2AFGFR1NPC1MEN1HPGD | |
| Hydrochloric Acid SCHEMBL7245719 | 0.83 | SIRT2 (0.49) | KMT2AFGFR1NPC1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1615896-B1 | NOVEL BENZIMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THESE COMPOUNDS | NEUROSEARCH AS (DK) | 2008-04-23 | — | — | EP | claimed |