Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 14/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2653616 | 0.93 | KMT2A (0.50) | KMT2AFGFR1NPC1MEN1HPGD | |
| SCHEMBL2651654 | 0.92 | FGFR1 (0.48) | KMT2AFGFR1NPC1MEN1HPGD | |
| SCHEMBL2653245 | 0.88 | KMT2A (0.51) | KMT2AFGFR1NPC1MEN1HPGD | |
| SCHEMBL4701541 | 0.87 | KMT2A (0.48) | KMT2AFGFR1NPC1MEN1HPGD | |
| SCHEMBL2654163 | 0.86 | KMT2A (0.47) | KMT2AFGFR1NPC1MEN1HPGD | |
| SCHEMBL2653620 | 0.86 | KMT2A (0.49) | KMT2AFGFR1NPC1MEN1HPGD | |
| SCHEMBL2652333 | 0.86 | FGFR1 (0.54) | KMT2AFGFR1NPC1MEN1HPGD | |
| SCHEMBL2652367 | 0.86 | FGFR1 (0.47) | KMT2AFGFR1NPC1MEN1HPGD | |
| SCHEMBL2652874 | 0.84 | SMN1; SMN2 (0.47) | KMT2AFGFR1NPC1MEN1HPGD | |
| SCHEMBL2648585 | 0.82 | HPGD (0.49) | KMT2AFGFR1NPC1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1615896-B1 | NOVEL BENZIMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THESE COMPOUNDS | NEUROSEARCH AS (DK) | 2008-04-23 | — | — | EP | claimed |
| US-20060241101-A1 | Novel benzimidazole derivatives and pharmaceutical compositions comprising these compounds | NEUSEARCH A/S (DK) | 2006-10-26 | — | — | US | claimed |
| EP-1615896-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THESE COMPOUNDS | NEUROSEARCH A/S (DK) | 2006-01-18 | — | — | EP | claimed |
| WO-2004089912-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THESE COMPOUNDS | NEUROSEARCH A/S (DK) | 2004-10-21 | — | — | WO | claimed |
| EP-1615896-B1 | NOVEL BENZIMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THESE COMPOUNDS | NEUROSEARCH AS (DK) | 2008-04-23 | — | — | EP | disclosed |
| US-20060241101-A1 | Novel benzimidazole derivatives and pharmaceutical compositions comprising these compounds | NEUSEARCH A/S (DK) | 2006-10-26 | — | — | US | disclosed |
| EP-1615896-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THESE COMPOUNDS | NEUROSEARCH A/S (DK) | 2006-01-18 | — | — | EP | disclosed |
| WO-2004089912-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THESE COMPOUNDS | NEUROSEARCH A/S (DK) | 2004-10-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060241101-A1 | Novel benzimidazole derivatives and pharmaceutical compositions comprising these compounds | GABRA2, GABRA1, GABRA5 | KMT2A 2056/4885FGFR1 2849/4885NPC1 3809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.