Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 6/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10982614 | 0.92 | AHR (0.58) | AHRLMNAMAPTHTTBLM | |
| SCHEMBL22180420 | 0.88 | AHR (0.47) | AHRLMNAMAPTHTTBLM | |
| SCHEMBL9778403 | 0.86 | AHR (0.59) | AHR | |
| SCHEMBL18199785 | 0.86 | AHR (0.59) | AHRLMNAMAPTHTTBLM | |
| SCHEMBL18199790 | 0.81 | AHR (0.47) | AHRLMNAMAPTHTTBLM | |
| SCHEMBL9778273 | 0.74 | NOX1 (0.40) | AHRLMNAMAPTCA12CA9 | |
| SCHEMBL11820541 | 0.73 | RECQL (0.39) | AHR | |
| SCHEMBL203042 | 0.73 | SNCA (0.40) | AHRMAPTSNCA | |
| SCHEMBL31121327 | 0.73 | SNCA (0.40) | AHRMAPTSNCA | |
| SCHEMBL2932917 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012003642-A1 | FUSED TRICYCLIC COMPOUNDS AND USE THEREOF FOR TREATING VIRAL DISEASES | MERCK SHARP & DOHME CORP. (US) | 2012-01-12 | — | — | WO | disclosed |