Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | AHR | P35869 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CYBB | P04839 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | NOX3 | Q9HBY0 | 1/20 | 0.40 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5358787 | 0.90 | MAPT (0.46) | NOX1MAPTMEN1KMT2ACYBB | |
| SCHEMBL11820541 | 0.83 | RECQL (0.39) | NOX1AHRMEN1KMT2AALOX15 | |
| SCHEMBL9778322 | 0.83 | NOX1 (0.51) | NOX1MAPTMEN1KMT2ACYBB | |
| SCHEMBL14468403 | 0.83 | CYP2A6 (0.49) | NOX1MAPTMEN1KMT2ACYBB | |
| SCHEMBL11820507 | 0.81 | AHR (0.37) | NOX1AHRMEN1KMT2AALOX15 | |
| SCHEMBL14446398 | 0.79 | MAPT (0.38) | NOX1MAPTMEN1KMT2ACYBB | |
| SCHEMBL11552722 | 0.79 | MAOA (0.47) | NOX1MAPTMEN1KMT2ACYBB | |
| SCHEMBL9778282 | 0.78 | MAPT (0.42) | NOX1MAPTMEN1KMT2ACYBB | |
| SCHEMBL47016 | 0.74 | AHR (0.56) | MAPTAHRSNCALMNACA12 | |
| SCHEMBL17559554 | 0.74 | NPC1 (0.37) | NOX1MAPTLMNAMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5036067-A | Enzyme inhibotors | MERCK & CO., INC. (US) | 1991-07-30 | — | — | US | disclosed |