SCHEMBL4701900

SCHEMBL4701900

CC1=Cc2ccccc2C1C1=C(C)C(C)c2cccc(-c3cc(C(C)(C)C)cc(C(C)(C)C)c3)c21

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
RXRA P19793 1/20 0.30
RXRB P28702 1/20 0.30
PTAFR P25105 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28860850 0.73 POLB (0.32) KDM4EGAAMAPTRXRARXRB
Hydrochloric Acid SCHEMBL8678158 0.71 EDNRB (0.30)
SCHEMBL1453463 0.71 PTAFR (0.32) PTAFR
SCHEMBL15809342 0.70
SCHEMBL1454171 0.70 PTAFR (0.31) PTAFR
SCHEMBL1454074 0.70 PTAFR (0.31) PTAFR
SCHEMBL1454464 0.69 PTAFR (0.33) PTAFR
SCHEMBL15809260 0.69
SCHEMBL6925960 0.68 RXRA (0.33) KDM4EGAAMAPTRXRARXRB
SCHEMBL4650856 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1971621-A1 PREPARATION OF SUBSTITUTED BRIDGED INDENYL AND RELATED LIGANDS ExxonMobil Chemical Patents Inc. (US) 2008-09-24 EP disclosed
WO-2007070045-A1 PREPARATION OF SUBSTITUTED BRIDGED INDENYL AND RELATED LIGANDS EXXONMOBIL CHEMICAL PATENTS, INC. (US) 2007-06-21 WO disclosed