Phthalimide

Phthalimide

SCHEMBL4702746

O=C1NC(=O)c2ccccc21.c1ccc2[nH]cnc2c1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 1/20 0.54
CASP3 P42574 1/20 0.47
CASP2 P42575 1/20 0.47
CASP7 P55210 1/20 0.47
CASP6 P55212 1/20 0.47
CASP8 Q14790 1/20 0.47
IDO1 P14902 1/20 0.46
TDO2 P48775 1/20 0.46
PARP1 P09874 4/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
PDPK1 O15530 1/20 0.46
CA12 O43570 1/20 0.46
ALOX15 P16050 1/20 0.46
CA9 Q16790 1/20 0.46
TNKS2 Q9H2K2 1/20 0.46
QPCT Q16769 3/20 0.44
QPCTL Q9NXS2 1/20 0.44
ALDH1A1 P00352 2/20 0.41
KDM4E B2RXH2 1/20 0.41
HPGD P15428 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Anthraquinone SCHEMBL28686015 0.85 IDO1 (0.55) GSK3BCASP7IDO1TDO2PARP1
Benzimidazole SCHEMBL29358377 0.82
Benzimidazole SCHEMBL29408372 0.82
Benzimidazole SCHEMBL6009 0.82
Benzimidazole SCHEMBL10931770 0.82 SMN1; SMN2 (0.50) IDO1TDO2PARP1SMN1; SMN2PDPK1
Benzimidazole SCHEMBL461969 0.82 SMN1; SMN2 (0.50) IDO1TDO2PARP1SMN1; SMN2PDPK1
Benzimidazole SCHEMBL23673327 0.80 SMN1; SMN2 (0.48) IDO1TDO2PARP1SMN1; SMN2PDPK1
Benzimidazole SCHEMBL21046391 0.80
Benzimidazole SCHEMBL5131535 0.80
Benzimidazole SCHEMBL22551123 0.80 SMN1; SMN2 (0.48) IDO1TDO2PARP1SMN1; SMN2PDPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1158321-B1 Dichroic light polarizers with non-periodic arrangement of different polarizing elements NITTO DENKO CORP (JP) 2012-05-30 EP disclosed
EP-1158320-B1 Dichroic light polarizers NITTO DENKO CORP (JP) 2008-08-06 EP disclosed
EP-0792257-B1 MATERIAL FOR DICHROIC LIGHT POLARIZERS OPTIVA INC (US) 2003-04-09 EP disclosed
EP-1158321-A2 Dichroic light polarizers with non-periodic arrangement of different polarizing elements Optiva, Inc. (US) 2001-11-28 EP disclosed
EP-1158320-A2 Dichroic light polarizers Optiva, Inc. (US) 2001-11-28 EP disclosed
US-6049428-A COATING A SUBSTRATE WITH A SOLUTION OF AN ORGANIC DYE OCCURRING IN THE LYOTROPIC LIQUID-CRYSTAL STATE IN A SOLVENT WHILE SIMULTANEOUSLY ORIENTING THE DYE AND REMOVING THE SOLVENT OPTIVA, INC. (US) 2000-04-11 US disclosed
EP-0792257-A4 DICHROIC LIGHT POLARIZERS OPTIVA INC (US) 2000-01-19 EP disclosed
EP-0792257-A1 DICHROIC LIGHT POLARIZERS RUSSIAN TECHNOLOGY GROUP (US) 1997-09-03 EP disclosed
WO-1996016015-A1 DICHROIC LIGHT POLARIZERS RUSSIAN TECHNOLOGY GROUP (US) 1996-05-30 WO disclosed