Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 10/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | GABRP | O00591 | 1/20 | 0.48 |
| ▸ | GABRD | O14764 | 1/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.48 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.48 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.48 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.48 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.48 |
| ▸ | GABRE | P78334 | 1/20 | 0.48 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.48 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.48 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.48 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2653222 | 0.90 | FGFR1 (0.48) | FGFR1HPGDMAPTTP53GABRP | |
| SCHEMBL5781249 | 0.86 | FGFR1 (0.61) | FGFR1HPGDMAPTTP53THRB | |
| SCHEMBL2653965 | 0.86 | FGFR1 (0.56) | FGFR1HPGDMAPTTP53THRB | |
| SCHEMBL2651449 | 0.83 | HPGD (0.50) | FGFR1HPGDMAPTTP53KMT2A | |
| SCHEMBL5781635 | 0.83 | FGFR1 (0.59) | FGFR1HPGDMAPTTP53THRB | |
| SCHEMBL4703128 | 0.83 | FGFR1 (0.54) | FGFR1HPGDMAPTTP53THRB | |
| SCHEMBL4703386 | 0.81 | MCHR1 (0.47) | HPGDTHRB | |
| SCHEMBL2650483 | 0.81 | FGFR1 (0.48) | FGFR1HPGDMAPTTP53KMT2A | |
| SCHEMBL2648584 | 0.80 | KMT2A (0.47) | FGFR1HPGDMAPTTP53KMT2A | |
| SCHEMBL2650914 | 0.80 | HPGD (0.49) | FGFR1HPGDMAPTTP53KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1615896-B1 | NOVEL BENZIMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THESE COMPOUNDS | NEUROSEARCH AS (DK) | 2008-04-23 | — | — | EP | claimed |