Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 5/20 | 0.47 |
| ▸ | GLP1R | P43220 | 6/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5782346 | 0.93 | THRB (0.47) | MCHR1GLP1RTHRBPTGER4HPGD | |
| SCHEMBL5778385 | 0.90 | THRB (0.46) | MCHR1GLP1RTHRBPTGER4HPGD | |
| SCHEMBL4703387 | 0.87 | THRB (0.44) | MCHR1GLP1RTHRBPTGER4HPGD | |
| SCHEMBL4703168 | 0.87 | THRB (0.48) | GLP1RTHRBPTGER4HPGDHCAR3 | |
| SCHEMBL5815980 | 0.84 | LMNA (0.45) | MCHR1THRBPTGER4HPGDHCAR3 | |
| SCHEMBL4703390 | 0.82 | THRB (0.46) | GLP1RTHRBPTGER4HPGDHCAR3 | |
| SCHEMBL4703129 | 0.81 | FGFR1 (0.53) | THRBHPGD | |
| SCHEMBL4702408 | 0.81 | THRB (0.44) | THRBPTGER4HPGDHCAR3HSD17B10 | |
| SCHEMBL5777980 | 0.81 | THRB (0.49) | THRBPTGER4HPGDHCAR3HSD17B10 | |
| SCHEMBL2649188 | 0.80 | MCHR1 (0.53) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1615896-B1 | NOVEL BENZIMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THESE COMPOUNDS | NEUROSEARCH AS (DK) | 2008-04-23 | — | — | EP | claimed |