Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 6/20 | 0.42 |
| ▸ | CA4 | P22748 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18651237 | 0.91 | CA2 (0.42) | CA2CA4LMNACA12CA1 | |
| SCHEMBL3577810 | 0.80 | CA2 (0.47) | CA2CA4LMNACA12CA1 | |
| SCHEMBL3586845 | 0.80 | CA2 (0.47) | CA2CA4LMNACA12CA1 | |
| SCHEMBL3585070 | 0.80 | CA2 (0.47) | CA2CA4LMNACA12CA1 | |
| SCHEMBL4750255 | 0.79 | CA2 (0.68) | CA2CA4LMNACA12CA1 | |
| SCHEMBL18651229 | 0.78 | CA2 (0.45) | CA2CA4LMNACA12CA1 | |
| SCHEMBL23643738 | 0.77 | CA2 (0.54) | CA2CA4LMNACA12CA1 | |
| SCHEMBL3583041 | 0.77 | CA2 (0.63) | CA2CA4LMNACA12CA1 | |
| SCHEMBL3583044 | 0.77 | CA2 (0.63) | CA2CA4LMNACA12CA1 | |
| SCHEMBL18651243 | 0.74 | CA2 (0.48) | CA2CA4LMNACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1985618-A1 | Process for the preparation of brinzolamide and intermediates thereof | Duke Chem, S. A. (ES) | 2008-10-29 | — | — | EP | disclosed |