Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 12/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 9/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 9/20 | 0.40 |
| ▸ | PIM1 | P11309 | 7/20 | 0.40 |
| ▸ | GSK3B | P49841 | 7/20 | 0.40 |
| ▸ | PIK3C3 | Q8NEB9 | 3/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 9/20 | 0.40 |
| ▸ | JAK2 | O60674 | 3/20 | 0.35 |
| ▸ | JAK1 | P23458 | 3/20 | 0.35 |
| ▸ | TYK2 | P29597 | 3/20 | 0.35 |
| ▸ | JAK3 | P52333 | 3/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | POLQ | O75417 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12577375 | 0.85 | PIK3C3 (0.37) | PIK3CDPIK3CAPIK3CGPIK3C3PIK3CB | |
| SCHEMBL12577081 | 0.76 | PIK3CD (0.47) | PIK3CDPIK3CAPIK3CGPIM1GSK3B | |
| SCHEMBL457168 | 0.70 | PIK3CD (0.45) | PIK3CDPIK3CAPIK3CGPIM1GSK3B | |
| SCHEMBL459341 | 0.70 | PIK3CD (0.56) | PIK3CDPIK3CAPIK3CGPIM1GSK3B | |
| SCHEMBL457146 | 0.67 | PIK3CD (0.50) | PIK3CDPIK3CAPIK3CGPIM1GSK3B | |
| SCHEMBL1782640 | 0.64 | PIK3CA (0.46) | PIK3CDPIK3CAPIK3CGPIM1GSK3B | |
| SCHEMBL1781030 | 0.63 | PIK3CD (0.47) | PIK3CDPIK3CAPIK3CGPIM1GSK3B | |
| SCHEMBL1781032 | 0.63 | PIK3CD (0.47) | PIK3CDPIK3CAPIK3CGPIM1GSK3B | |
| SCHEMBL12574857 | 0.62 | PIK3CD (0.37) | PIK3CDPIK3CAPIK3CGPIM1GSK3B | |
| SCHEMBL1780999 | 0.62 | PIK3CD (0.46) | PIK3CDPIK3CAPIK3CGPIM1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012032065-A1 | INDAZOLE DERIVATIVES FOR USE IN THE TREATMENT OF INFLUENZA VIRUS INFECTION | GLAXO GROUP LIMITED (GB) | 2012-03-15 | — | — | WO | disclosed |
| WO-2011067364-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2011-06-09 | — | — | WO | disclosed |