Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 17/20 | 0.58 |
| ▸ | HTR2C | P28335 | 2/20 | 0.57 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14945579 | 0.83 | RBP4 (0.61) | RBP4HTR2CDRD3GRM2CYP2D6 | |
| SCHEMBL5007618 | 0.80 | HTR2C (0.75) | RBP4HTR2CDRD3GRM2CYP2D6 | |
| SCHEMBL7812713 | 0.80 | GRIN2D (0.42) | RBP4HTR2C | |
| SCHEMBL15118691 | 0.79 | RBP4 (0.57) | RBP4HTR2CDRD3GRM2CYP2D6 | |
| SCHEMBL13416041 | 0.77 | RBP4 (0.55) | RBP4HTR2CDRD3GRM2 | |
| SCHEMBL30090937 | 0.77 | RBP4 (0.62) | RBP4HTR2CCYP2D6CYP2C19 | |
| SCHEMBL19493700 | 0.77 | RBP4 (0.55) | RBP4HTR2CDRD3GRM2 | |
| SCHEMBL16103507 | 0.77 | RBP4 (0.62) | RBP4HTR2CCYP2D6CYP2C19 | |
| SCHEMBL25218964 | 0.77 | RBP4 (0.74) | RBP4CYP2D6CYP2C19 | |
| SCHEMBL1919230 | 0.77 | HTR2C (0.70) | RBP4HTR2CDRD3GRM2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1416933-B1 | SUBSTITUTED PIPERIDINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR | AMGEM INC (US) | 2008-01-02 | — | — | EP | disclosed |