Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 5/20 | 0.46 |
| ▸ | NOS3 | P29474 | 4/20 | 0.46 |
| ▸ | NOS2 | P35228 | 3/20 | 0.46 |
| ▸ | HRH2 | P25021 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4703789 | 1.00 | NOS1 (0.46) | NOS1NOS3NOS2HRH2HRH4 | |
| SCHEMBL4703632 | 0.91 | NOS1 (0.44) | NOS1NOS3NOS2HRH2HRH4 | |
| SCHEMBL4703636 | 0.91 | NOS1 (0.44) | NOS1NOS3NOS2HRH2HRH4 | |
| SCHEMBL4702018 | 0.90 | NOS1 (0.46) | NOS1NOS3NOS2 | |
| SCHEMBL4702008 | 0.90 | NOS1 (0.46) | NOS1NOS3NOS2 | |
| SCHEMBL4703798 | 0.85 | NOS1 (0.58) | NOS1NOS3NOS2 | |
| SCHEMBL4703799 | 0.85 | NOS1 (0.58) | NOS1NOS3NOS2 | |
| Hydrochloric Acid SCHEMBL5641814 | 0.84 | NOS1 (0.57) | NOS1NOS3NOS2 | |
| SCHEMBL4701645 | 0.83 | NOS1 (0.50) | NOS1NOS3NOS2 | |
| SCHEMBL4701628 | 0.83 | NOS1 (0.50) | NOS1NOS3NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1527068-B1 | NOVEL ARYLIMIDAZOLE DERIVATIVES, THEIR USE AS NO-SYNTASE INHIBITORS AND AS MODULATORS OF SODIUM CHANNELS | SOD CONSEILS RECH APPLIC (FR) | 2008-01-09 | — | — | EP | disclosed |