Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 2/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4886065 | 0.84 | KMT2A (0.54) | KMT2AALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL4705337 | 0.82 | ADORA2A (0.33) | KMT2AALDH1A1MEN1GAANPC1 | |
| SCHEMBL4704008 | 0.81 | IDO1 (0.36) | KMT2AALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL4705939 | 0.78 | KMT2A (0.41) | KMT2AALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL1573910 | 0.78 | KMT2A (0.41) | KMT2AALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL1573877 | 0.71 | KDM4E (0.41) | KMT2AALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL1573602 | 0.71 | KDM4E (0.51) | KMT2AALDH1A1MEN1NPSR1GAA | |
| SCHEMBL4703574 | 0.71 | TP53 (0.45) | KMT2AALDH1A1MEN1GAANPC1 | |
| SCHEMBL4705335 | 0.66 | GAA (0.46) | KMT2AALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL4704006 | 0.65 | GAA (0.45) | KMT2AALDH1A1MEN1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874741-A1 | AZOLE DERIVATIVES IN THE FORM OF LIPASE AND PHOSPHOLIPASE INHIBITORS | sanofi-aventis (FR) | 2008-01-09 | — | — | EP | disclosed |
| WO-2006111321-A1 | AZOLE DERIVATIVES IN THE FORM OF LIPASE AND PHOSPHOLIPASE INHIBITORS | SANOFI-AVENTIS (DE) | 2006-10-26 | — | — | WO | disclosed |