Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4704008 | 0.88 | IDO1 (0.36) | GRM5GAASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL4705335 | 0.84 | GAA (0.46) | GRM5GAAALDH1A1HPGDNPC1 | |
| SCHEMBL4704034 | 0.82 | KMT2A (0.41) | GAASMN1; SMN2ALDH1A1HPGDNPC1 | |
| SCHEMBL4704006 | 0.72 | GAA (0.45) | GRM5GAASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL1573877 | 0.67 | KDM4E (0.41) | GAASMN1; SMN2ALDH1A1HPGDMAPT | |
| SCHEMBL1573602 | 0.67 | KDM4E (0.51) | GAASMN1; SMN2ALDH1A1HPGDNPC1 | |
| SCHEMBL4703574 | 0.67 | TP53 (0.45) | GAASMN1; SMN2ALDH1A1HPGDNPC1 | |
| SCHEMBL1573825 | 0.66 | AXL (0.37) | GAASMN1; SMN2ALDH1A1HPGDNPC1 | |
| SCHEMBL4886065 | 0.66 | KMT2A (0.54) | GAASMN1; SMN2ALDH1A1HPGDNPC1 | |
| SCHEMBL1573910 | 0.64 | KMT2A (0.41) | GAASMN1; SMN2ALDH1A1HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874741-A1 | AZOLE DERIVATIVES IN THE FORM OF LIPASE AND PHOSPHOLIPASE INHIBITORS | sanofi-aventis (FR) | 2008-01-09 | — | — | EP | disclosed |
| WO-2006111321-A1 | AZOLE DERIVATIVES IN THE FORM OF LIPASE AND PHOSPHOLIPASE INHIBITORS | SANOFI-AVENTIS (DE) | 2006-10-26 | — | — | WO | disclosed |