Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 17/20 | 0.65 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.57 |
| ▸ | CCKAR | P32238 | 10/20 | 0.51 |
| ▸ | CBLB | Q13191 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4703582 | 0.91 | CCKBR (0.63) | CCKBRBDKRB1CCKARCBLB | |
| SCHEMBL6045926 | 0.87 | CCKBR (0.72) | CCKBRBDKRB1CCKAR | |
| SCHEMBL4705683 | 0.87 | CCKBR (0.64) | CCKBRBDKRB1CCKARCBLB | |
| SCHEMBL4704015 | 0.84 | CCKBR (0.62) | CCKBRBDKRB1CCKARCBLB | |
| SCHEMBL6045943 | 0.82 | CCKBR (0.71) | CCKBRBDKRB1CCKAR | |
| SCHEMBL9524959 | 0.80 | CCKBR (1.00) | CCKBRBDKRB1CCKARCBLB | |
| SCHEMBL643128 | 0.80 | CCKBR (1.00) | CCKBRBDKRB1CCKARCBLB | |
| SCHEMBL4704894 | 0.80 | CCKBR (0.65) | CCKBRBDKRB1CCKAR | |
| SCHEMBL4704031 | 0.79 | CCKBR (0.67) | CCKBRBDKRB1CCKAR | |
| SCHEMBL4705743 | 0.79 | CCKBR (0.67) | CCKBRBDKRB1CCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633348-B1 | 4- BROMO - 5 - (2- CHLORO - BENZOYLAMINO) - 1H - PYRAZOLE - 3 - CARBOXYLIC ACID AMIDE DERIVATIVES AND RELATED COMPOUNDS AS BRADYKININ B sb 1 /sb RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | ELAN PHARM INC (US) | 2008-10-08 | — | — | EP | claimed |