Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 12/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | BRS3 | P32247 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16938615 | 0.89 | CNR1 (0.54) | CNR1XDHMAP4K4CNR2MAPK1 | |
| SCHEMBL410543 | 0.83 | CNR1 (0.55) | CNR1XDHCNR2GRM4 | |
| SCHEMBL412004 | 0.76 | CNR1 (0.52) | CNR1CNR2 | |
| SCHEMBL441630 | 0.76 | CNR1 (0.52) | CNR1CNR2 | |
| SCHEMBL442354 | 0.71 | CNR1 (0.67) | CNR1CNR2 | |
| SCHEMBL27973515 | 0.70 | CHEK1 (0.54) | — | |
| SCHEMBL442533 | 0.70 | MAP4K4 (0.55) | CNR1MAP4K4 | |
| SCHEMBL2702006 | 0.68 | MARS1 (0.46) | CNR1MAP4K4 | |
| SCHEMBL411076 | 0.67 | CNR1 (0.67) | CNR1MAP4K4CNR2 | |
| SCHEMBL5355700 | 0.66 | CNR1 (0.67) | CNR1MAP4K4CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012032018-A1 | HETEROARYLMETHYL AMIDES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-03-15 | — | — | WO | disclosed |