Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 5/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | F2R | P25116 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL457722 | 0.78 | NTRK1 (0.41) | NTRK1DPP4NPY5RF2R | |
| SCHEMBL457724 | 0.78 | NTRK1 (0.41) | NTRK1DPP4NPY5RF2R | |
| SCHEMBL470735 | 0.77 | NTRK1 (0.42) | NTRK1DPP4NPY5RF2R | |
| SCHEMBL14730347 | 0.77 | NTRK1 (0.36) | NTRK1DPP4NPY5RF2R | |
| SCHEMBL12064789 | 0.75 | NTRK1 (0.40) | NTRK1DPP4NPY5RF2R | |
| SCHEMBL470570 | 0.75 | NTRK1 (0.43) | NTRK1DPP4NPY5RF2R | |
| SCHEMBL458712 | 0.75 | NTRK1 (0.41) | USP30NTRK1DPP4NPY5RF2R | |
| SCHEMBL610961 | 0.75 | NTRK1 (0.41) | USP30NTRK1DPP4NPY5RF2R | |
| SCHEMBL14723500 | 0.74 | NTRK1 (0.42) | NTRK1DPP4NPY5RF2R | |
| SCHEMBL14730294 | 0.74 | NTRK1 (0.42) | NTRK1DPP4NPY5RF2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |