Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 3/20 | 0.36 |
| ▸ | VNN1 | O95497 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
| ▸ | F2R | P25116 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | GPR6 | P46095 | 2/20 | 0.31 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14730345 | 0.88 | NTRK1 (0.40) | NTRK1VNN1MCHR1HDAC1 | |
| SCHEMBL14730301 | 0.84 | MCHR1 (0.40) | VNN1HDAC3HDAC2DPP4MCHR1 | |
| SCHEMBL14730296 | 0.83 | NTRK1 (0.38) | NTRK1HDAC3HDAC2F2RNPY5R | |
| SCHEMBL470478 | 0.77 | USP30 (0.39) | NTRK1DPP4F2RNPY5R | |
| SCHEMBL457724 | 0.76 | NTRK1 (0.41) | NTRK1DPP4F2RNPY5R | |
| SCHEMBL457722 | 0.76 | NTRK1 (0.41) | NTRK1DPP4F2RNPY5R | |
| SCHEMBL6128115 | 0.75 | NTRK1 (0.41) | NTRK1HDAC3HDAC2DPP4F2R | |
| SCHEMBL14722979 | 0.75 | NTRK1 (0.41) | NTRK1HDAC3HDAC2DPP4F2R | |
| SCHEMBL14723036 | 0.75 | RET (0.41) | NTRK1 | |
| SCHEMBL14730344 | 0.75 | RET (0.41) | NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026587-A1 | 1,4 DISUBSTITUTED PYRROLIDINE - 3 - YL -AMINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2013-02-28 | — | — | WO | disclosed |