Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 17/20 | 0.57 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3030359 | 0.83 | LTA4H (0.76) | LTA4HMEN1KMT2A | |
| SCHEMBL3036726 | 0.83 | LTA4H (0.76) | LTA4HMEN1KMT2A | |
| SCHEMBL3035375 | 0.80 | SRD5A2 (0.61) | LTA4HSRD5A2MEN1KMT2A | |
| SCHEMBL3040865 | 0.79 | LTA4H (0.77) | LTA4H | |
| SCHEMBL3040863 | 0.79 | LTA4H (0.77) | LTA4H | |
| SCHEMBL3035452 | 0.76 | LTA4H (0.65) | LTA4HMEN1KMT2A | |
| SCHEMBL3039567 | 0.75 | LTA4H (0.64) | LTA4HMEN1KMT2A | |
| SCHEMBL5312324 | 0.74 | LTA4H (0.72) | LTA4HMEN1KMT2A | |
| SCHEMBL3032189 | 0.73 | LTA4H (0.78) | LTA4HSRD5A2 | |
| SCHEMBL3045089 | 0.72 | LTA4H (1.00) | LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1976828-A1 | DIAMINE DERIVATIVES AS INHIBITORS OF LEUKOTRIENE A4 HYDROLASE | Schering Aktiengesellschaft (DE) | 2008-10-08 | — | — | EP | claimed |
| WO-2007079078-A1 | DIAMINE DERIVATIVES AS INHIBITORS OF LEUKOTRIENE A4 HYDROLASE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-07-12 | — | — | WO | claimed |