Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 19/20 | 0.66 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.50 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL384756 | 0.89 | GPR119 (0.66) | GPR119CYP4F2CYP4A11 | |
| SCHEMBL1092728 | 0.86 | GPR119 (0.66) | GPR119CYP4F2CYP4A11 | |
| SCHEMBL12064714 | 0.86 | GPR119 (0.59) | GPR119 | |
| SCHEMBL11956857 | 0.83 | GPR119 (0.84) | GPR119 | |
| SCHEMBL457366 | 0.82 | GPR119 (0.60) | GPR119 | |
| SCHEMBL387351 | 0.81 | GPR119 (0.59) | GPR119 | |
| SCHEMBL387205 | 0.80 | GPR119 (0.77) | GPR119CYP4F2CYP4A11 | |
| SCHEMBL387260 | 0.80 | GPR119 (0.71) | GPR119CYP4F2CYP4A11 | |
| SCHEMBL13160668 | 0.80 | GPR119 (0.52) | GPR119 | |
| SCHEMBL13160671 | 0.80 | GPR119 (0.56) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |
| WO-2010103333-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2010-09-16 | — | — | WO | disclosed |