SCHEMBL4705239

SCHEMBL4705239

O=C1c2ccccc2-c2ccc3c4ccc5c6c(ccc(c7ccc1c2c37)c64)-c1ccc(O)c(O)c1C5=O

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.68
MEN1 O00255 7/20 0.68
KMT2A Q03164 7/20 0.68
MCL1 Q07820 6/20 0.68
MAPK1 P28482 5/20 0.68
BCL2 P10415 5/20 0.68
MAOA P21397 4/20 0.68
ALDH1A1 P00352 4/20 0.68
KDM4E B2RXH2 4/20 0.68
CYP3A4 P08684 4/20 0.68
HPGD P15428 4/20 0.68
ALOX15 P16050 3/20 0.68
RECQL P46063 3/20 0.68
HSD17B10 Q99714 3/20 0.68
SMN1; SMN2 Q16637 3/20 0.68
APEX1 P27695 2/20 0.68
ALOX12 P18054 2/20 0.68
DAPK1 P53355 2/20 0.68
CYP1B1 Q16678 2/20 0.68
TTR P02766 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9491124 0.91 MAPT (0.63) MAPTMEN1KMT2AMCL1MAPK1
SCHEMBL87593 0.86 MAOA (0.55) MAPTMEN1KMT2AMCL1MAPK1
SCHEMBL7983966 0.85 MAPT (0.85) MAPTMEN1KMT2AMCL1MAPK1
SCHEMBL31177134 0.85 MAPT (0.85) MAPTMEN1KMT2AMCL1MAPK1
SCHEMBL11094126 0.84 MAPT (0.49) MAPTMEN1KMT2AMCL1MAPK1
Athraquinones A SCHEMBL4972786 0.82 MAPT (1.00) MAPTMEN1KMT2AMCL1MAPK1
Athraquinones A SCHEMBL29373337 0.82 MAPT (1.00) MAPTMEN1KMT2AMCL1MAPK1
Athraquinones A SCHEMBL18614 0.82 MAPT (1.00) MAPTMEN1KMT2AMCL1MAPK1
Athraquinones A SCHEMBL21114402 0.82 MAPT (1.00) MAPTMEN1KMT2AMCL1MAPK1
SCHEMBL2990513 0.82 MEN1 (0.78) MAPTMEN1KMT2AMCL1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1158321-B1 Dichroic light polarizers with non-periodic arrangement of different polarizing elements NITTO DENKO CORP (JP) 2012-05-30 EP disclosed
EP-1158320-B1 Dichroic light polarizers NITTO DENKO CORP (JP) 2008-08-06 EP disclosed
EP-1158321-A2 Dichroic light polarizers with non-periodic arrangement of different polarizing elements Optiva, Inc. (US) 2001-11-28 EP disclosed
EP-1158320-A2 Dichroic light polarizers Optiva, Inc. (US) 2001-11-28 EP disclosed
US-6049428-A COATING A SUBSTRATE WITH A SOLUTION OF AN ORGANIC DYE OCCURRING IN THE LYOTROPIC LIQUID-CRYSTAL STATE IN A SOLVENT WHILE SIMULTANEOUSLY ORIENTING THE DYE AND REMOVING THE SOLVENT OPTIVA, INC. (US) 2000-04-11 US disclosed
EP-0792257-A4 DICHROIC LIGHT POLARIZERS OPTIVA INC (US) 2000-01-19 EP disclosed
EP-0792257-A1 DICHROIC LIGHT POLARIZERS RUSSIAN TECHNOLOGY GROUP (US) 1997-09-03 EP disclosed
WO-1996016015-A1 DICHROIC LIGHT POLARIZERS RUSSIAN TECHNOLOGY GROUP (US) 1996-05-30 WO disclosed
US-4882095-A Preparation of alkoxy(iso)violanthrenediones BASF AKTIENGESELLSCHAFT (DE) 1989-11-21 US disclosed