Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.38 |
| ▸ | SORD | Q00796 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12989025 | 0.88 | ACHE (0.38) | HRH3SORDGPR119PRMT5HRH4 | |
| SCHEMBL24126682 | 0.84 | HRH3 (0.37) | HRH3GPR119PRMT5RORCKCNH2 | |
| SCHEMBL8513708 | 0.83 | SMO (0.42) | GPR119HRH4THRBKDM4E | |
| SCHEMBL29504721 | 0.82 | PANK3 (0.46) | HRH3SORDGPR119KCNH2KDM4E | |
| SCHEMBL19434903 | 0.82 | PANK3 (0.46) | HRH3SORDGPR119KCNH2KDM4E | |
| SCHEMBL9925927 | 0.81 | MAPT (0.47) | GPR119HRH4ALDH1A1 | |
| SCHEMBL23107223 | 0.81 | HRH3 (0.49) | HRH3PRMT5RORC | |
| SCHEMBL23103856 | 0.81 | HRH3 (0.49) | HRH3PRMT5RORC | |
| SCHEMBL11919298 | 0.80 | CKS1B (0.49) | HRH3GPR119HRH4 | |
| SCHEMBL26684557 | 0.78 | HRH3 (0.35) | HRH3SORDHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |