Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 0.57 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.53 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL647349 | 1.00 | DPP4 (0.57) | DPP4DPP9IP6K1 | |
| SCHEMBL647410 | 0.86 | DPP4 (0.58) | DPP4DPP9IP6K1 | |
| SCHEMBL648349 | 0.86 | DPP4 (0.73) | DPP4DPP9IP6K1 | |
| SCHEMBL645765 | 0.84 | DPP4 (0.56) | DPP4DPP9 | |
| SCHEMBL645608 | 0.84 | DPP4 (0.56) | DPP4DPP9 | |
| SCHEMBL646326 | 0.84 | DPP4 (0.74) | DPP4DPP9 | |
| SCHEMBL5516636 | 0.84 | DPP4 (0.74) | DPP4DPP9 | |
| SCHEMBL647250 | 0.83 | DPP4 (0.55) | DPP4DPP9 | |
| SCHEMBL646735 | 0.83 | DPP4 (0.59) | DPP4DPP9 | |
| SCHEMBL648128 | 0.82 | DPP4 (0.75) | DPP4DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1560811-B9 | PHARMACEUTICAL COMPOSITIONS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV) | ABBOTT LAB (US) | 2008-03-05 | — | — | EP | disclosed |
| EP-1560811-B1 | PHARMACEUTICAL COMPOSITIONS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV) | ABBOTT LAB (US) | 2007-08-01 | — | — | EP | disclosed |