Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 14/20 | 0.40 |
| ▸ | ALKBH1 | Q13686 | 2/20 | 0.35 |
| ▸ | RORC | P51449 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14730177 | 0.85 | EIF2AK4 (0.31) | — | |
| SCHEMBL470593 | 0.81 | GPR119 (0.37) | GPR119 | |
| SCHEMBL470518 | 0.75 | ACACB (0.30) | — | |
| SCHEMBL14730225 | 0.72 | GPR119 (0.33) | GPR119 | |
| SCHEMBL14730171 | 0.72 | GPR119 (0.32) | GPR119 | |
| SCHEMBL21564375 | 0.72 | CKS1B (0.56) | GPR119ALKBH1 | |
| SCHEMBL14730203 | 0.72 | GPR119 (0.32) | GPR119 | |
| SCHEMBL14730213 | 0.72 | GPR119 (0.33) | GPR119 | |
| SCHEMBL14730214 | 0.72 | GPR119 (0.33) | GPR119 | |
| SCHEMBL14730317 | 0.71 | GPR119 (0.34) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |