Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.36 |
| ▸ | DPP4 | P27487 | 17/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 12/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 11/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 13/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12064750 | 0.84 | MCHR1 (0.36) | MCHR1DPP4DPP8DPP9KCNH2 | |
| SCHEMBL470692 | 0.84 | MCHR1 (0.36) | MCHR1DPP4DPP8DPP9KCNH2 | |
| SCHEMBL461833 | 0.83 | MCHR1 (0.36) | MCHR1DPP4DPP8DPP9KCNH2 | |
| SCHEMBL470695 | 0.82 | DPP4 (0.39) | MCHR1DPP4DPP8DPP9KCNH2 | |
| SCHEMBL462518 | 0.81 | DPP4 (0.43) | MCHR1DPP4DPP8DPP9KCNH2 | |
| SCHEMBL470671 | 0.81 | MCHR1 (0.37) | MCHR1DPP4DPP8DPP9KCNH2 | |
| SCHEMBL462389 | 0.81 | MCHR1 (0.41) | MCHR1DPP4DPP8DPP9KCNH2 | |
| SCHEMBL470656 | 0.80 | ALOX5AP (0.34) | DPP4DPP8DPP9KCNH2DPP7 | |
| Hydrochloric Acid SCHEMBL462388 | 0.80 | MCHR1 (0.40) | MCHR1DPP4DPP8DPP9KCNH2 | |
| SCHEMBL470520 | 0.79 | DPP4 (0.42) | MCHR1DPP4DPP8DPP9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |