SCHEMBL470695 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	DPP4	P27487	14/20	0.39

▸	DPP8	Q6V1X1	10/20	0.39

▸	DPP9	Q86TI2	8/20	0.39

▸	MCHR1	Q99705	5/20	0.39

▸	KCNH2	Q12809	3/20	0.39

▸	DPP7	Q9UHL4	7/20	0.33

▸	GPR119	Q8TDV5	2/20	0.33

▸	FFAR1	O14842	1/20	0.32

▸	FAP	Q12884	2/20	0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL470902	0.93	DPP4 (0.34)	DPP4DPP8DPP9MCHR1KCNH2
SCHEMBL470671	0.93	MCHR1 (0.37)	DPP4DPP8DPP9MCHR1KCNH2
SCHEMBL462540	0.92	DPP4 (0.34)	DPP4DPP8DPP9MCHR1KCNH2
SCHEMBL12064853	0.91	ALDH1A1 (0.34)	DPP4DPP8DPP9MCHR1KCNH2
SCHEMBL470636	0.90	MCHR1 (0.37)	DPP4DPP8DPP9MCHR1KCNH2
SCHEMBL470662	0.89	GPR119 (0.33)	DPP4DPP8DPP9KCNH2DPP7
SCHEMBL461833	0.89	MCHR1 (0.36)	DPP4DPP8DPP9MCHR1KCNH2
SCHEMBL12064750	0.87	MCHR1 (0.36)	DPP4DPP8DPP9MCHR1KCNH2
SCHEMBL470692	0.87	MCHR1 (0.36)	DPP4DPP8DPP9MCHR1KCNH2
SCHEMBL470624	0.86	GPR119 (0.33)	DPP4DPP8DPP9KCNH2DPP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2011147951-A1	CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS	PROSIDION LIMITED (GB)	2011-12-01	—	—	WO	disclosed