Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.36 |
| ▸ | GPR183 | P32249 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL470858 | 0.82 | GPR119 (0.39) | GPR119GPR183KCNH2 | |
| SCHEMBL12064844 | 0.82 | GPR119 (0.38) | GPR119GPR183KCNH2 | |
| SCHEMBL14730182 | 0.79 | GPR119 (0.35) | GPR119GPR183KCNH2 | |
| SCHEMBL470614 | 0.79 | GPR119 (0.38) | GPR119GPR183 | |
| SCHEMBL14730298 | 0.76 | ALOX5AP (0.34) | GPR119 | |
| SCHEMBL14730247 | 0.76 | — | — | |
| SCHEMBL14730185 | 0.76 | GPR119 (0.34) | GPR119GPR183KCNH2 | |
| SCHEMBL12064754 | 0.74 | GPR119 (0.44) | GPR119GPR183KCNH2 | |
| SCHEMBL12064777 | 0.74 | AOC3 (0.33) | GPR119GPR183 | |
| SCHEMBL14730316 | 0.73 | GPR119 (0.34) | GPR119GPR183 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |