Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 9/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 5/20 | 0.32 |
| ▸ | MALT1 | Q9UDY8 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9978183 | 0.77 | CNR1 (0.39) | CNR1KCNH2SCN5ASCN2ASCN10A | |
| SCHEMBL9931687 | 0.73 | CNR1 (0.39) | CNR1SCN5ACNR2MAPTEGLN1 | |
| SCHEMBL15512416 | 0.73 | CNR1 (0.39) | CNR1SCN5ACNR2MAPTEGLN1 | |
| SCHEMBL9931688 | 0.73 | CNR1 (0.39) | CNR1SCN5ACNR2MAPTEGLN1 | |
| SCHEMBL412410 | 0.73 | CNR1 (0.44) | CNR1KCNH2SCN5ASCN2ASCN10A | |
| SCHEMBL410983 | 0.73 | CNR1 (0.48) | CNR1KCNH2SCN5ASCN2ASCN10A | |
| SCHEMBL410639 | 0.73 | CNR1 (0.44) | CNR1KCNH2SCN5ASCN2ASCN10A | |
| SCHEMBL441810 | 0.73 | CNR1 (0.44) | CNR1KCNH2SCN5ASCN2ASCN10A | |
| SCHEMBL9973791 | 0.72 | CNR1 (0.53) | CNR1CNR2 | |
| SCHEMBL9978235 | 0.72 | CNR2 (0.47) | CNR1KCNH2SCN5ASCN2ASCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012032018-A1 | HETEROARYLMETHYL AMIDES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-03-15 | — | — | WO | disclosed |