Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | GCGR | P47871 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9931688 | 0.86 | CNR1 (0.39) | CNR1CNR2SLC6A3GCGRCHRM1 | |
| SCHEMBL9931687 | 0.86 | CNR1 (0.39) | CNR1CNR2SLC6A3GCGRCHRM1 | |
| SCHEMBL15512416 | 0.86 | CNR1 (0.39) | CNR1CNR2SLC6A3GCGRCHRM1 | |
| SCHEMBL9931435 | 0.79 | KMO (0.47) | CNR1SLC6A3MEN1MAPTHTT | |
| SCHEMBL470674 | 0.77 | CNR1 (0.43) | CNR1CNR2MAPTSCN5AKCNH2 | |
| SCHEMBL9978227 | 0.77 | SLC6A3 (0.41) | CNR1SLC6A3MEN1MAPTHTT | |
| SCHEMBL9932341 | 0.77 | CNR1 (0.55) | CNR1CNR2SCN5AKCNH2SCN2A | |
| SCHEMBL9935929 | 0.77 | CNR1 (0.41) | CNR1CNR2SLC6A3MEN1KMT2A | |
| SCHEMBL9978235 | 0.76 | CNR2 (0.47) | CNR1CNR2SCN5AKCNH2SCN2A | |
| SCHEMBL9931452 | 0.75 | CNR1 (0.53) | CNR1CNR2SCN5AKCNH2SCN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012080144-A1 | OXIME COMPOUNDS AS HDL-CHOLESTEROL RAISING AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2012-06-21 | — | — | WO | disclosed |