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SCHEMBL470693

SCHEMBL470693

CC[C@H](C)S(=O)(=O)N1CCC([C@H](C)Oc2cnc(N3C[C@H](C4=CC(F)C(F)C=C4F)[C@@H](N)C3)nc2)CC1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ GPR119 Q8TDV5 1/20 0.31
▸ DPP4 P27487 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12064845 0.87 GPR119 (0.31) GPR119
SCHEMBL470864 0.86 GPR119 (0.30) GPR119
SCHEMBL459777 0.84 DPP4 (0.43) DPP4
SCHEMBL459776 0.84 DPP4 (0.43) DPP4
SCHEMBL470638 0.84 DPP4 (0.43) DPP4
SCHEMBL470595 0.72 GPR119 (0.33) GPR119
SCHEMBL470672 0.72 ACACB (0.35) —
SCHEMBL470687 0.71 GPR119 (0.39) GPR119
SCHEMBL470622 0.71 DPP4 (0.41) DPP4
SCHEMBL459778 0.71 DPP4 (0.41) GPR119DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011147951-A1 CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS PROSIDION LIMITED (GB) 2011-12-01 — — WO disclosed