Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1921377 | 0.78 | NOTUM (0.41) | NOTUML3MBTL1 | |
| SCHEMBL1921376 | 0.72 | NOTUM (0.40) | NOTUML3MBTL1 | |
| SCHEMBL3828488 | 0.65 | — | — | |
| SCHEMBL1197799 | 0.63 | L3MBTL1 (0.47) | NOTUML3MBTL1 | |
| SCHEMBL10231735 | 0.60 | L3MBTL1 (0.49) | NOTUML3MBTL1 | |
| SCHEMBL2657681 | 0.59 | L3MBTL1 (0.48) | NOTUML3MBTL1 | |
| SCHEMBL1196334 | 0.59 | NOTUM (0.39) | NOTUML3MBTL1 | |
| SCHEMBL15783459 | 0.58 | NOTUM (0.43) | NOTUM | |
| SCHEMBL15337360 | 0.57 | NOTUM (0.43) | NOTUML3MBTL1 | |
| SCHEMBL5542210 | 0.57 | KCNN4 (0.55) | NOTUML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981854-A1 | ARYLPROPIONAMIDE, ARYLACRYLAMIDE, ARYLPROPYNAMIDE, OR ARYLMETHYLUREA ANALOGS AS FACTOR XIA INHIBITORS | Brystol-Myers Squibb Company (US) | 2008-10-22 | — | — | EP | disclosed |
| WO-2007070826-A1 | ARYLPROPIONAMIDE, ARYLACRYLAMIDE, ARYLPROPYNAMIDE, OR ARYLMETHYLUREA ANALOGS AS FACTOR XIA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-06-21 | — | — | WO | disclosed |