Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Cefmenoxime. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 5/20 | 0.99 |
| ▸ | PGR | P06401 | 2/20 | 0.99 |
| ▸ | PPARG | P37231 | 2/20 | 0.76 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.76 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.76 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.76 |
| ▸ | DAO | P14920 | 1/20 | 0.76 |
| ▸ | SNCA | P37840 | 1/20 | 0.76 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.76 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.75 |
| ▸ | HTR2C | P28335 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 5/20 | 0.69 |
| ▸ | ALB | P02768 | 1/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.68 |
| ▸ | APEX1 | P27695 | 4/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.68 |
| ▸ | RECQL | P46063 | 2/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cefmenoxime SCHEMBL192782 | 1.00 | NR1I2 (0.99) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| Cefmenoxime SCHEMBL192780 | 1.00 | NR1I2 (0.99) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| Cefmenoxime SCHEMBL27487467 | 1.00 | NR1I2 (0.99) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| Cefmenoxime SCHEMBL3252593 | 0.99 | NR1I2 (1.00) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| Cefmenoxime SCHEMBL9659869 | 0.99 | NR1I2 (1.00) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| Cefmenoxime SCHEMBL8768620 | 0.99 | NR1I2 (1.00) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| Cefmenoxime SCHEMBL10633730 | 0.99 | NR1I2 (1.00) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| Cefmenoxime SCHEMBL1813696 | 0.99 | NR1I2 (1.00) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| Cefmenoxime SCHEMBL152861 | 0.99 | NR1I2 (1.00) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| Cefmenoxime SCHEMBL10492342 | 0.99 | NR1I2 (1.00) | NR1I2PGRPPARGSLC22A6SLC22A8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874455-A | THIOL OR DISULFIDE DERIVATIVES FOR CATARACTS | GAKKO HOJIN KINKI DAIGAKU (JP) | 1999-02-23 | — | — | US | claimed |
| US-20210290432-A1 | KIT FOR PRODUCING KERATOCONJUNCTIVAL COVER SHEET AND METHOD FOR PRODUCING KERATOCONJUNCTIVAL COVER SHEET | OSAKA UNIVERSITY (JP) | 2021-09-23 | — | — | US | disclosed |
| EP-3536352-A1 | KERATOCONJUNCTIVAL COVER SHEET AND METHOD FOR PRODUCING KERATOCONJUNCTIVAL COVER SHEET | Osaka University (JP) | 2019-09-11 | — | — | EP | disclosed |
| EP-1618894-B1 | COMPOSITION FOR INJECTION | TAKEDA PHARMACEUTICALS CO (JP) | 2018-06-13 | — | — | EP | disclosed |
| US-9526735-B2 | Method for suppressing surgical site infection and column to be used for the method | ASAHI KASEI MEDICAL CO., LTD. (JP) | 2016-12-27 | — | — | US | disclosed |
| US-20140179659-A1 | METHOD FOR SUPPRESSING SURGICAL SITE INFECTION AND COLUMN TO BE USED FOR THE METHOD | ASAHI KASEI MEDICAL CO., LTD. (JP) | 2014-06-26 | — | — | US | disclosed |
| US-8708945-B2 | Method for suppressing surgical site infection and column to be used for the method | ASAHI KASEI MEDICAL CO., LTD. (JP) | 2014-04-29 | — | — | US | disclosed |
| US-20080260710-A1 | Method for Suppressing Surgical Site Infection and Column to be Used for the Method | ASAHI KASEI MEDICAL CO., LTD. (JP) | 2008-10-23 | — | — | US | disclosed |
| US-7399485-B1 | Rapidly Disintegrable solid preparation | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-07-15 | — | — | US | disclosed |
| US-20070254031-A1 | Rapidly disintegrable solid preparation | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-11-01 | — | — | US | disclosed |
| US-5308347-A | Transfusion device | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-05-03 | — | — | US | disclosed |
| US-5261902-A | Fluid container assembly | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-11-16 | — | — | US | disclosed |
| EP-0335378-B1 | FLUID CONTAINER | NISSHO CORPORATION (JP) | 1993-10-13 | — | — | EP | disclosed |
| EP-0538891-A1 | Infusion container | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-04-28 | — | — | EP | disclosed |
| EP-0533171-A1 | Transfusion device | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-24 | — | — | EP | disclosed |
| EP-0516117-A2 | Fluid container assembly | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-12-02 | — | — | EP | disclosed |
| US-5051406-A | Protein as a binder for drugs | NIPPON HYPOX LABORATORIES INCORPORATED (JP) | 1991-09-24 | — | — | US | disclosed |
| US-4936841-A | Fluid container | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-06-26 | — | — | US | disclosed |
| EP-0335378-A2 | Fluid container | NISSHO CORPORATION (JP) | 1989-10-04 | — | — | EP | disclosed |
| EP-0326618-A1 | MEDICINAL COMPOSITION CONTAINING ALBUMIN AS CARRIER AND PROCESS FOR ITS PREPARATION | NIPPON HYPOX LABORATORIES INCORPORATED (JP) | 1989-08-09 | — | — | EP | disclosed |