Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 7/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL470616 | 0.88 | DPP4 (0.36) | GPR119 | |
| Hydrochloric Acid SCHEMBL462961 | 0.87 | DPP4 (0.36) | GPR119 | |
| SCHEMBL122214 | 0.84 | GPR119 (0.42) | GPR119NTRK1 | |
| SCHEMBL149038 | 0.81 | GPR119 (0.43) | GPR119NTRK1 | |
| SCHEMBL145121 | 0.80 | GPR119 (0.43) | GPR119NTRK1 | |
| SCHEMBL612843 | 0.78 | GPR119 (0.35) | GPR119NTRK1LMNANR1H2 | |
| SCHEMBL610917 | 0.77 | GPR119 (0.47) | GPR119LMNATP53 | |
| SCHEMBL470486 | 0.77 | NTRK1 (0.36) | GPR119NTRK1NR1H2 | |
| SCHEMBL149552 | 0.76 | GPR119 (0.38) | GPR119NTRK1 | |
| SCHEMBL121467 | 0.76 | GPR119 (0.38) | GPR119NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |