Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.54 |
| ▸ | MAPT | P10636 | 9/20 | 0.54 |
| ▸ | GFER | P55789 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | RAD52 | P43351 | 2/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3011234 | 0.82 | ALDH1A1 (0.59) | ALDH1A1MAPTGFERLMNAMAPK1 | |
| SCHEMBL13724795 | 0.81 | MAPT (0.50) | ALDH1A1MAPTGFERLMNAMAPK1 | |
| SCHEMBL17265648 | 0.80 | ALDH1A1 (0.77) | ALDH1A1MAPTGFERLMNAMAPK1 | |
| SCHEMBL25091068 | 0.80 | ALDH1A1 (0.49) | ALDH1A1MAPTGFERLMNAMAPK1 | |
| SCHEMBL18410807 | 0.80 | MAPT (0.49) | ALDH1A1MAPTGFERLMNAMAPK1 | |
| SCHEMBL22171267 | 0.79 | ALDH1A1 (0.46) | ALDH1A1MAPTGFERLMNAMAPK1 | |
| SCHEMBL14898020 | 0.77 | MAPT (0.67) | ALDH1A1MAPTGFERLMNAMAPK1 | |
| SCHEMBL3442442 | 0.77 | ALDH1A1 (0.67) | ALDH1A1MAPTGFERLMNAMAPK1 | |
| SCHEMBL7038110 | 0.77 | ALDH1A1 (0.67) | ALDH1A1MAPTGFERLMNAMAPK1 | |
| SCHEMBL4918379 | 0.76 | ALDH1A1 (0.65) | ALDH1A1MAPTGFERLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1902048-A1 | OXAZOLIDINONE CARBOXAMIDES CONTAINING AZETIDINE AND CYCLOBUTANE AS ANTIBACTERIAL AGENTS | Pharmacia & Upjohn Company LLC (US) | 2008-03-26 | — | — | EP | disclosed |
| WO-2007004037-A1 | OXAZOLIDINONE CARBOXAMIDES CONTAINING AZETIDINE AND CYCLOBUTANE AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2007-01-11 | — | — | WO | disclosed |