⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14410498 | 0.72 | — | — | |
| SCHEMBL17025205 | 0.70 | — | — | |
| SCHEMBL13271185 | 0.69 | — | — | |
| SCHEMBL28746805 | 0.65 | EPHX1 (0.33) | — | |
| SCHEMBL17363065 | 0.65 | — | — | |
| SCHEMBL350254 | 0.64 | EPHX1 (0.31) | — | |
| SCHEMBL5118 | 0.64 | EPHX1 (0.31) | — | |
| SCHEMBL5709 | 0.64 | EPHX1 (0.31) | — | |
| SCHEMBL3813341 | 0.64 | EPHX1 (0.31) | — | |
| SCHEMBL27992718 | 0.64 | EPHX1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981877-A1 | N-HYDROXYACRYLAMIDE COMPOUNDS | Astellas Pharma Inc. (JP) | 2008-10-22 | — | — | EP | claimed |
| WO-2007091703-A1 | N-HYDROXYACRYLAMIDE COMPOUNDS | ASTELLAS PHARMA INC. (JP) | 2007-08-16 | — | — | WO | claimed |