Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8665200 | 0.69 | — | — | |
| SCHEMBL8664368 | 0.69 | — | — | |
| SCHEMBL8664366 | 0.69 | — | — | |
| SCHEMBL1005162 | 0.59 | — | — | |
| SCHEMBL11524261 | 0.55 | — | — | |
| SCHEMBL28621789 | 0.55 | — | — | |
| SCHEMBL23555421 | 0.55 | MEN1 (0.36) | KDM1A | |
| SCHEMBL22260111 | 0.55 | KDM1A (0.53) | KDM1A | |
| SCHEMBL12056060 | 0.54 | THRB (0.32) | — | |
| SCHEMBL27913763 | 0.54 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012031307-A1 | PLEUROMUTILIN DERIVATIVES FOR USE IN THE TREATMENT OF DISEASES MEDIATED BY MICROBES | NABRIVA THERAPEUTICS AG (AT) | 2012-03-15 | — | — | WO | disclosed |