SCHEMBL4708465

SCHEMBL4708465

Cc1cc(-c2ccc(N3CC(C)OC3=O)cc2F)cnc1N1CCS(=O)(=O)CC1

nearest known ligand 0.50

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CALML3 P27482 6/20 0.50
MAOA P21397 12/20 0.49
MAOB P27338 2/20 0.49
CYP2C19 P33261 2/20 0.46
CYP2C9 P11712 1/20 0.46
CYP3A4 P08684 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13944972 0.91 CALML3 (0.62) CALML3MAOAMAOBCYP2C19CYP2C9
SCHEMBL4708462 0.90 CALML3 (0.49) CALML3MAOAMAOBCYP2C19CYP2C9
SCHEMBL4760556 0.87 CALML3 (0.49) CALML3MAOAMAOBCYP2C19CYP2C9
SCHEMBL4709151 0.85 MAOA (0.50) CALML3MAOAMAOBCYP2C19CYP2C9
SCHEMBL4169168 0.85 MAOA (0.61) CALML3MAOAMAOBCYP2C19CYP3A4
SCHEMBL4169162 0.85 MAOA (0.61) CALML3MAOAMAOBCYP2C19CYP3A4
SCHEMBL13945052 0.84 CALML3 (0.50) CALML3MAOAMAOBCYP2C19CYP2C9
SCHEMBL4177290 0.84 MAOA (0.52) CALML3MAOAMAOBCYP2C19CYP2C9
SCHEMBL13944980 0.84 MAOA (0.66) MAOACYP2C9CYP3A4
SCHEMBL4177288 0.84 MAOA (0.52) CALML3MAOAMAOBCYP2C19CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1912980-A2 OXAZOLIDINONES BEARING ANTIMICROBIAL ACTIVITY COMPOSITION AND METHODS OF PREPARATION Wockhardt Limited (IN) 2008-04-23 EP claimed
WO-2007023507-A2 OXAZOLIDINONES BEARING ANTIMICROBIAL ACTIVITY COMPOSITION AND METHODS OF PREPARATION WOCKHARDT LIMITED (IN) 2007-03-01 WO claimed