Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 12/20 | 1.00 |
| ▸ | SPHK1 | Q9NYA1 | 12/20 | 1.00 |
| ▸ | MAPT | P10636 | 4/20 | 1.00 |
| ▸ | MEN1 | O00255 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | CETP | P11597 | 3/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 3/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 3/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 1.00 |
| ▸ | GMNN | O75496 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | GLA | P06280 | 2/20 | 1.00 |
| ▸ | POLB | P06746 | 2/20 | 1.00 |
| ▸ | THRB | P10828 | 2/20 | 1.00 |
| ▸ | CXCR5 | P32302 | 2/20 | 1.00 |
| ▸ | CCR6 | P51684 | 2/20 | 1.00 |
| ▸ | BLM | P54132 | 2/20 | 1.00 |
| ▸ | UBE2N | P61088 | 2/20 | 1.00 |
| ▸ | TP53 | P04637 | 2/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 2/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sphingosine SCHEMBL1471985 | 1.00 | SPHK2 (1.00) | SPHK2SPHK1MAPTMEN1KMT2A | |
| SCHEMBL12330736 | 1.00 | SPHK2 (1.00) | SPHK2SPHK1MAPTMEN1KMT2A | |
| Sphingosine SCHEMBL15650079 | 1.00 | SPHK2 (1.00) | SPHK2SPHK1MAPTMEN1KMT2A | |
| Sphingosine SCHEMBL22911044 | 1.00 | SPHK2 (1.00) | SPHK2SPHK1MAPTMEN1KMT2A | |
| SCHEMBL22986843 | 1.00 | SPHK2 (1.00) | SPHK2SPHK1MAPTMEN1KMT2A | |
| SCHEMBL21428474 | 1.00 | SPHK2 (1.00) | SPHK2SPHK1MAPTMEN1KMT2A | |
| SCHEMBL22986939 | 1.00 | SPHK2 (1.00) | SPHK2SPHK1MAPTMEN1KMT2A | |
| SCHEMBL20819097 | 1.00 | SPHK2 (1.00) | SPHK2SPHK1MAPTMEN1KMT2A | |
| Sphingosine SCHEMBL21114357 | 1.00 | SPHK2 (1.00) | SPHK2SPHK1MAPTMEN1KMT2A | |
| SCHEMBL21428477 | 1.00 | SPHK2 (1.00) | SPHK2SPHK1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9732030-B2 | Process for the preparation of fingolimod and its salts | SHILPA MEDICARE LIMITED (IN) | 2017-08-15 | — | — | US | disclosed |
| US-9732030-B2 | Process for the preparation of fingolimod and its salts | SHILPA MEDICARE LIMITED (IN) | 2017-08-15 | — | — | US | disclosed |
| US-20170204122-A1 | METHODS FOR THE SYNTHESIS OF SPHINGOMYELINS AND DIHYDROSPHINGOMYELINS | CERENIS THERAPEUTICS HOLDING SA (FR) | 2017-07-20 | — | — | US | disclosed |
| US-20170204122-A1 | METHODS FOR THE SYNTHESIS OF SPHINGOMYELINS AND DIHYDROSPHINGOMYELINS | CERENIS THERAPEUTICS HOLDING SA (FR) | 2017-07-20 | — | — | US | disclosed |
| US-9708354-B2 | Methods for the synthesis of sphingomyelins and dihydrosphingomyelins | CERENIS THERAPEUTICS HOLDING SA (FR) | 2017-07-18 | — | — | US | disclosed |
| US-9643915-B2 | Methods for the synthesis of sphingomyelins and dihydrosphingomyelins | CERENIS THERAPEUTICS HOLDING SA (FR) | 2017-05-09 | — | — | US | disclosed |
| US-20160075634-A1 | METHODS FOR THE SYNTHESIS OF SPHINGOMYELINS AND DIHYDROSPHINGOMYELINS | CERENIS THERAPEUTICS HOLDING SA (FR) | 2016-03-17 | — | — | US | disclosed |
| US-20150344409-A1 | PROCESS FOR THE PREPARATION OF FINGOLIMOD AND ITS SALTS | SHILPA MEDICARE LIMITED (IN) | 2015-12-03 | — | — | US | disclosed |
| US-20150344409-A1 | PROCESS FOR THE PREPARATION OF FINGOLIMOD AND ITS SALTS | SHILPA MEDICARE LIMITED (IN) | 2015-12-03 | — | — | US | disclosed |
| US-20140316154-A1 | METHODS FOR THE SYNTHESIS OF SPHINGOMYELINS AND DIHYDROSPHINGOMYELINS | CERENIS THERAPEUTICS HOLDING SA (FR) | 2014-10-23 | — | — | US | disclosed |
| WO-2014140787-A2 | METHODS FOR THE SYNTHESIS OF SPHINGOMYELINS AND DIHYDROSPHINGOMYELINS | CERENIS THERAPEUTICS HOLDING SA (FR) | 2014-09-18 | — | — | WO | disclosed |
| US-20140275590-A1 | METHODS FOR THE SYNTHESIS OF SPHINGOMYELINS AND DIHYDROSPHINGOMYELINS | CERENIS THERAPEUTICS HOLDING SA (FR) | 2014-09-18 | — | — | US | disclosed |
| US-20140275590-A1 | METHODS FOR THE SYNTHESIS OF SPHINGOMYELINS AND DIHYDROSPHINGOMYELINS | CERENIS THERAPEUTICS HOLDING SA (FR) | 2014-09-18 | — | — | US | disclosed |
| WO-2014111836-A1 | PROCESS FOR PREPARATION OF FINGOLIMOD AND ITS SALTS | SHILPA MEDICARE LIMITED (IN) | 2014-07-24 | — | — | WO | disclosed |
| US-20130281739-A1 | FINGOLIMOD POLYMORPHS AND THEIR PROCESSES | SHILPA PHARMA INC. | 2013-10-24 | — | — | US | disclosed |
| US-20130281739-A1 | FINGOLIMOD POLYMORPHS AND THEIR PROCESSES | SHILPA PHARMA INC. | 2013-10-24 | — | — | US | disclosed |
| US-20120142765-A1 | Sphingosine-bound siRNA | SYLENTIS S.A.U. (ES) | 2012-06-07 | — | — | US | disclosed |
| EP-1767644-A1 | Microbial strains producing sphingosine | Cosmoferm B.V. (NL) | 2007-03-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150344409-A1 | PROCESS FOR THE PREPARATION OF FINGOLIMOD AND ITS SALTS | S1PR4, S1PR1, S1PR5 | SPHK2 7/4885SPHK1 6/4885MAPT 1743/4885 |
| US-20140316154-A1 | METHODS FOR THE SYNTHESIS OF SPHINGOMYELINS AND DIHYDROSPHINGOMYELINS | SGMS1, SGMS2, CERS2 | SPHK2 13/4885SPHK1 12/4885MAPT 2159/4885 |
| US-20130281739-A1 | FINGOLIMOD POLYMORPHS AND THEIR PROCESSES | S1PR4, S1PR5, IFNAR1 | SPHK2 10/4885SPHK1 9/4885MAPT 1053/4885 |
| US-20160075634-A1 | METHODS FOR THE SYNTHESIS OF SPHINGOMYELINS AND DIHYDROSPHINGOMYELINS | SGMS1, SGMS2, CERS2 | SPHK2 13/4885SPHK1 12/4885MAPT 2159/4885 |
| US-20140275590-A1 | METHODS FOR THE SYNTHESIS OF SPHINGOMYELINS AND DIHYDROSPHINGOMYELINS | SGMS1, SGMS2, CERS2 | SPHK2 13/4885SPHK1 12/4885MAPT 2159/4885 |
| US-20170204122-A1 | METHODS FOR THE SYNTHESIS OF SPHINGOMYELINS AND DIHYDROSPHINGOMYELINS | SGMS1, SGMS2, CERS2 | SPHK2 13/4885SPHK1 12/4885MAPT 2159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.