SCHEMBL470893

SCHEMBL470893

C#CCOCc1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.61
LMNA P02545 1/20 0.45
ALDH1A1 P00352 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
IDO1 P14902 1/20 0.44
AGXT P21549 1/20 0.43
NAAA Q02083 1/20 0.42
CA1 P00915 4/20 0.41
CA2 P00918 2/20 0.41
CA7 P43166 2/20 0.41
CA9 Q16790 2/20 0.41
KDM4E B2RXH2 1/20 0.41
POLB P06746 1/20 0.41
TACR1 P25103 2/20 0.40
MMP2 P08253 1/20 0.40
MMP12 P39900 1/20 0.40
NPC1 O15118 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19460555 0.98 TSHR (0.58) TSHRLMNAALDH1A1SMN1; SMN2IDO1
SCHEMBL3821073 0.90 TSHR (0.54) TSHRLMNAALDH1A1SMN1; SMN2IDO1
SCHEMBL23567271 0.90 TSHR (0.54) TSHRLMNAALDH1A1SMN1; SMN2IDO1
SCHEMBL3423851 0.88 TSHR (0.42) TSHRLMNAALDH1A1SMN1; SMN2IDO1
SCHEMBL20423790 0.88 NAAA (0.53) TSHRLMNAALDH1A1SMN1; SMN2IDO1
SCHEMBL4180174 0.86 TSHR (0.50) TSHRLMNANAAA
SCHEMBL17758006 0.85 NAAA (0.50) TSHRNAAAMMP2
SCHEMBL6508653 0.81 TSHR (0.67) TSHRLMNAALDH1A1SMN1; SMN2IDO1
SCHEMBL8749381 0.80 TSHR (0.46) TSHRLMNAALDH1A1SMN1; SMN2IDO1
SCHEMBL3637694 0.80 TSHR (0.65) TSHRLMNAALDH1A1SMN1; SMN2IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 483 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118994491-A Photocurable composition for stereolithography, stereolithography method using the same, polymer assembly formed by the stereolithography method, and device comprising the polymer assembly 罗杰斯公司 2024-11-22 CN claimed
EP-4121802-B1 HIGH REFRACTIVE INDEX SILOXANE INSERT MATERIALS FOR EMBEDDED CONTACT LENSES ALCON INC (CH) 2024-07-17 EP claimed
US-12018154-B2 Rubber composition offering high stiffness and low hysteresis THE GOODYEAR TIRE & RUBBER COMPANY (US) 2024-06-25 US claimed
US-11834569-B2 Rubber composition and a rubber product THE GOODYEAR TIRE & RUBBER COMPANY (US) 2023-12-05 US claimed
EP-4279278-A2 PHOTOCURABLE COMPOSITIONS FOR STEREOLITHOGRAPHY, STEREOLITHOGRAPHY METHODS USING THE COMPOSITIONS, POLYMER COMPONENTS FORMED BY THE STEREOLITHOGRAPHY METHODS, AND A DEVICE INCLUDING THE POLYMER COMPONENTS Rogers Corporation (US) 2023-11-22 EP claimed
US-11787878-B2 Photocurable compositions for stereolithography, method of forming the compositions, stereolithography methods using the compositions, polymer components formed by the stereolithography methods, and a device including the polymer components ROGERS CORPORATION (US) 2023-10-17 US claimed
CN-113493576-B Rubber composition and rubber product 固特异轮胎和橡胶公司 2023-05-23 CN claimed
EP-3888940-B1 A RUBBER COMPOSITION AND A RUBBER PRODUCT GOODYEAR TIRE & RUBBER (US) 2023-01-11 EP claimed
US-20220298270-A1 PHOTOCURABLE COMPOSITIONS FOR STEREOLITHOGRAPHY, METHOD OF FORMING THE COMPOSITIONS, STEREOLITHOGRAPHY METHODS USING THE COMPOSITIONS, POLYMER COMPONENTS FORMED BY THE STEREOLITHOGRAPHY METHODS, AND A DEVICE INCLUDING THE POLYMER COMPONENTS JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT 2022-09-22 US claimed
EP-3728339-B1 COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS AMO Ireland (IE) 2022-07-06 EP claimed
EP-2192932-B1 OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS ALCON INC (CH) 2011-05-04 EP claimed
EP-2192930-B1 OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS CONTAINING AN ALKYL ETHOXYLATE ALCON INC (CH) 2011-04-13 EP claimed
EP-2176243-B1 OPHTHALMIC LENS MATERIALS CONTAINING CHROMOPHORES THAT ABSORB BOTH UV AND SHORT WAVELENGTH VISIBLE LIGHT ALCON INC (CH) 2011-02-09 EP claimed
EP-2139871-B1 UV-ABSORBERS FOR OPHTHALMIC LENS MATERIALS ALCON INC (CH) 2010-09-01 EP claimed
EP-1210380-B1 FOLDABLE OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS ALCON INC (CH) 2005-03-16 EP claimed
EP-0973768-B1 AZOLE COMPOUNDS, THEIR PRODUCTION AND THEIR USE TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2003-07-09 EP claimed
EP-0865339-B1 METALLOPROTEINASE INHIBITORS BRITISH BIOTECH PHARM (GB) 2003-01-22 EP claimed
EP-0873304-B1 METALLOPROTEINASE INHIBITORS BRITISH BIOTECH PHARM (GB) 2001-09-05 EP claimed
EP-0793641-B1 METALLOPROTEINASE INHIBITORS BRITISH BIOTECH PHARM (GB) 1999-04-21 EP claimed
EP-0093620-B1 FUNGICIDAL N-PHENYLCARBAMATES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-01-07 EP claimed