SCHEMBL471

SCHEMBL471

BrCc1ccccc1-c1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.60
KMT2A Q03164 1/20 0.50
ALDH1A1 P00352 4/20 0.48
MAPK1 P28482 1/20 0.48
PDCD1 Q15116 1/20 0.47
CD274 Q9NZQ7 1/20 0.47
HTR7 P34969 1/20 0.43
FOLH1 Q04609 1/20 0.43
CYP11B1 P15538 1/20 0.43
CYP11B2 P19099 1/20 0.43
HSD17B10 Q99714 2/20 0.42
HPGD P15428 1/20 0.42
BCL2L1 Q07817 1/20 0.42
CYP2A6 P11509 1/20 0.42
TRPA1 O75762 1/20 0.42
TSHR P16473 1/20 0.42
KCNA5 P22460 1/20 0.42
KCNH2 Q12809 1/20 0.42
PTGER1 P34995 1/20 0.39
PTGER4 P35408 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31163822 1.00 DPP4 (0.60) DPP4KMT2AALDH1A1MAPK1PDCD1
SCHEMBL2902236 0.98 DPP4 (0.58) DPP4KMT2AALDH1A1MAPK1PDCD1
SCHEMBL31753971 0.91 DPP4 (0.50) DPP4KMT2AALDH1A1MAPK1PDCD1
SCHEMBL28961512 0.90 DPP4 (0.48) DPP4KMT2AALDH1A1MAPK1PDCD1
SCHEMBL376955 0.88 DPP4 (0.48) DPP4KMT2AALDH1A1MAPK1PDCD1
SCHEMBL1309773 0.84 ALDH1A1 (0.48) DPP4KMT2AALDH1A1MAPK1PDCD1
SCHEMBL1309790 0.84 ALDH1A1 (0.43) DPP4KMT2AALDH1A1MAPK1PDCD1
SCHEMBL31454260 0.83 DPP4 (0.41) DPP4KMT2AALDH1A1MAPK1PDCD1
SCHEMBL1038470 0.82 HTR2C (0.44) DPP4KMT2AHTR7KCNA5KCNH2
SCHEMBL5858344 0.82 DPP4 (0.47) DPP4KMT2AALDH1A1MAPK1PDCD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1360 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114814041-B Method for detecting brominated alkanes genotoxic impurities in telmisartan by adopting liquid chromatography-mass spectrometer 浙江金立源药业有限公司 2024-05-10 CN claimed
CN-117654298-A Polyamine acid-base resistant composite filter membrane, preparation method and application thereof 中国科学院苏州纳米技术与纳米仿生研究所 2024-03-08 CN claimed
CN-114907376-B Molecular machine based on bi-m-benzene-32-crown-10 main body cave ether and preparation method thereof 浙江大学杭州国际科创中心 2024-01-23 CN claimed
CN-117304258-A Application of polypeptide 湖南大学 2023-12-29 CN claimed
CN-117186178-A Polypeptide and preparation method thereof 湖南大学 2023-12-08 CN claimed
CN-117126236-A Organophosphorus pesticide detection polypeptide probe and preparation and application thereof 西华大学 2023-11-28 CN claimed
CN-113751076-B Bis-imidazolium palladium-supported porous organic polymer catalyst and preparation method and application thereof 南京工业大学 2023-09-19 CN claimed
CN-116082447-A Polypeptide and preparation method thereof 湖南大学 2023-05-09 CN claimed
CN-115181248-A Porous organic polymer with quaternary ammonium salt structure and preparation method and application thereof 东莞理工学院 2022-10-14 CN claimed
CN-114975904-A Polyoxometalate-based viologen polymer derived carbide composite material and preparation method and application thereof 上海应用技术大学 2022-08-30 CN claimed
CN-101648839-B Green synthesis method of bromomethyl biphenyl compound BEIJING SECOND PHARMACEUTICAL CO LTD 2012-05-02 CN claimed
CN-101768035-A Method for preparing and recovering aromatic methyl diphenyl compound ZHEJIANG HUAHAI PHARM CO LTD 2010-07-07 CN claimed
CN-101648839-A Green synthesis method of bromomethylbiphenyl compound BEIJING SECOND PHARMACEUTICAL 2010-02-17 CN claimed
CN-101597243-A The synthetic method of a kind of 2-cyano group-4 '-bromomethylbiphenyl ASYMCHEM LIFE SCIENCE TIANJIN (CN) 2009-12-09 CN claimed
CN-100441567-C Acrylic ester and methyl acrylic ester kind side chain type luminous polymer and its synthesis UNIV SUZHOU (CN) 2008-12-10 CN claimed
CN-1786106-A Acrylic ester and methyl acrylic ester kind side chain type luminous polymer and its synthesis UNIV SUZHOU (CN) 2006-06-14 CN claimed
CN-1765938-A Uses of 4-bromomethylbiphenyl and 2-substituted 4'-bromomethylbiphenyl UNIV SOOCHOW (CN) 2006-05-03 CN claimed
CN-1415614-A Technique for synthesizing Irbesartan CHANG AO SCIENCE AND TECHNOLOG (CN) 2003-05-07 CN claimed
WO-2001044147-A1 PROCESS FOR THE PREPARATION OF 2-METHYLBIPHENYL AND OF 2-PHENYLBENZYL BROMIDE ALBEMARLE CORPORATION (US) 2001-06-21 WO claimed
WO-1999033788-A2 METHOD FOR PRODUCING AROMATIC BROMOMETHYL BIPHENYL COMPOUNDS GREAT LAKES CHEMICAL KONSTANZ GMBH (DE) 1999-07-08 WO claimed